We need your feedback! The following questions are optional and will only be used to get an idea of how we can make our summer program more beneficial to participants.
Your abstract should:
Include a short description of what you did and learned
Be interesting and informative
Be written for a broad audience: explain key concepts briefly and spell out abbreviations on first use
Include why your work is important (Don't assume the reader knows)
Include only numbers that are most important (Don’t get caught up in numbers)
Examples of past student abstracts:
Word Puzzles Versus Pictures: A Comparison of Studying Pictures and Solving Anagrams to Improve Memory in Patients with Alzheimer's DiseaseAlzheimer’s Disease (AD) is a form of dementia that results in impairments in episodic memory. Patients with AD will often forget events or objects that they have previously encountered, or even exhibit false memories, causing them to misremember information that may have not actually ever occurred. Much of research dealing with AD patients looks for ways of improving their daily lives and finding strategies to improve memory and reduce false memory.The present study compares two methods that have been known to improve memory in young healthy adults, and evaluates their effectiveness in improving true memory while reducing false memory in patients with AD. The experiment consists of two conditions. In the Picture condition, patients will study a set of pictures with the associated word for each picture, for a later memory test. In the Word condition, patients are asked to solve simple anagrams and then are asked to remember the resulting word once the anagram is solved. Evidence shows that healthy individuals can improve their memory if they are able to generate information themselves. Pictures, in addition to words, provide the subject with a distinct image that recruits multiple parts of the brain. Generating information may also recruit additional areas of the brain that are similar to those used to encode pictures. The results of this experiment will help determine if generating information helps patients better remember information, and may provide a method for patients to improve their overall memory.
Evolutionary Origins of Toll-Like Receptor Signaling in Nematostella VectensisThe innate immune system is the most primitive branch of the immune system and is responsible for recognizing pathogens and eliciting responses such as inflammation and antimicrobial peptide production in many organisms. Toll-like receptors (TLRs) are transmembrane receptors that have been characterized in organisms from insects to humans. TLRs detect molecules expressed by microbial pathogens and activate the NF-κB transcription factor signaling pathway to turn on innate immune effector genes. Recent genome and transcriptome sequencing have identified TLRs in organisms more basal to insects, but the biological roles of these basal TLRs are not well understood. In this project, we are characterizing a TLR-like protein in the sea anemone Nematostella vectensis, a model organism for the phylum Cnidaria. The Nv-TLR structure is consistent with those in higher organisms. In cell culture-based reporter assays, Nv-TLR can activate mammalian NF-κB and Nv-TLR can bind to mammalian NF-κB signal transduction adaptor proteins MAL and MyD88. In anemones, Nv-TLR and Nv-NF-κB (and most intermediate TLR to NF-κB signaling proteins) are expressed in cnidocytes, both in the body column and in a nematostella-specific circulating organelle called the nematosome. Furthermore, we show that the pathway can be activated by the biologically relevant bacterium Vibrio coralliilyticus and purified flagellin from Salmonella typhimurium. These data suggest that a TLR-to-NF-κB pathway is functionally conserved in cnidarians. Moreover, these studies provide insight into the evolutionary basis of vertebrate innate immunity, and shed light on how simple organisms respond at the molecular level to environmental and biological stressors.
Abstracts are limited to 250 words.